· Gabapentin was developed as an anti-seizure medication but is also useful in the treatment of chronic pain. It’s mechanism of action is not fully understood, but it is thought to decrease the release of certain neurotransmitters in the brain that are associated with the sensation of pain.
· Works best combined with other pain relievers such as NSAIDS, tramadol, and/or amantadine.
· Generally well tolerated, but may cause sedation and/or incoordination.
· Best to start with a low dose and increase as needed. Dogs with advanced arthritis and muscle atrophy may have more trouble with coordination, walking, and standing.