· Amantadine was developed as an antiviral medication but also is useful in the treatment of chronic pain. It works by partially blocking a receptor within the central nervous system that is associated with pain pathways.
· Works best combined with other pain relievers such as NSAIDS, gabapentin, and/or tramadol.
· Generally well tolerated, but may cause gastrointestinal effects (diarrhoea) or some agitation, both of which tend to resolve as the pet adjusts to the medication.
· Use with caution and decrease dose in patients with liver or kidney dysfunction, congestive heart failure, and seizure disorders.